History Of Dna

 Two scientists named, Rosalind Franklin and Maurice Wilkins, decided to try to make a watch crystal of the desoxyribonucleic acid molecule.  If they could becharm DNA to crystallize, then they could make an roentgenogram pattern, thus resulting in understanding how DNA works.  These two scientists were roaring and obtained an x-ray pattern.  The pattern appeared to contain rungs, like those on a ladder between to strands that are side by side.  It too showed by an X shape that DNA had a spiral shape. Another Scientist was Erwin Chargaff. To understand the DNA molecule better scientists were onerous to make a pretence to understand how it works and what it does.  In the 1940s another scientist named Erwin Chargaff noticed a pattern in the tote ups of the four bases: adenine, gee, cytosine, and thymine.  He took samples of DNA of different cells and found that the amount of adenine was almost equal to the amount of thymine, and that the amount of guanine was almost equal to the amount of cytosine Thus you could register: A=T and G=C.  This discovery later became Chargaffs Rule. Lastly In 1953 two scientists, James Watson and Francis Crick, were trying to put option together a model of DNA.  When they saw Franklin and
Wilkins picture of the roentgenogram they had enough information to make an accurate model.



  They created a model that has not been changed much since then.  Their model showed a double gyre with little rungs connecting the two strands. These rungs were the bases of a nucleotide (see nucleic acids).  At beginning Watson and Crick were set back with a problem, how to bond the bases together, and how to settle the problem of the sizes of the bases.  Adenine and Guanine were purines having two carbon-nitrogen rings in their structures.  Thymine and Cytosine were pyrimidines having one carbon-nitrogen ring in its structure. If DNA were to have its bases pair up so that the purines and the pyrimidines were together, then it would flavour wobly and crooked.  Watson and Crick then found that if they paired Thymine...If you want to get a full essay, order it on our website: Ordercustompaper.com



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