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Acta Obstet Gynecol Scand 2004: 83: 850856 Printed in Denmark. All rights reserved

Copyright # Acta Obstet Gynecol Scand 2004

Acta Obstetricia et Gynecologica Scandinavica

ORIGINAL ARTICLE

Side-effects of endocrine replacement therapy and influence on pattern of use among women decrepit 4564 years. The Norwegian Women and Cancer (NOWAC) study 1997
KJERSTI BAKKEN1, ANNE ELISE EGGEN2
AND

EILIV LUND1

From the Institutes of 1Community medicament and 2Pharmacy, University of Tromsø, Tromsø, Norway

Acta Obstet Gynecol Scand 2004; 83: 850856. # Acta Obstet Gynecol Scand 83 2004 Background. Use of hormone replacement therapy (hormone replacement therapy) increase considerably in Norway during the 1990s. The aim of this study was to investigate reasons for first and discontinuing hormone replacement therapy use and examine the prevalence of side-effects and what impact they had on pattern of use. Methods. The Norwegian Woman and Cancer (NOWAC) study is a population-based, prospective study based on mailed questionnaires to women 3070 years. This report is limited to a random essay of 4996 Norwegian women aged 4564 years who participated in 1997 (response rate 62%).



The questionnaire included detailed questions about HRT: reasons for starting and stopping, type of preparation, duration of use and side-effects experienced. Results. Most women started HRT to ameliorate climacteric complaints (75.9%). Only 8.7% had prevention of osteoporosis as the however reason for therapy. Mean duration of use was 4.9 years among incumbent users. Side-effects were reported by 43% of the ever users, nearly fractional of them reporting more than one side-effect. Weight gain was the or so frequent stated sideeffect (56.3%), although not statistically significant in association with HRT. Among ever users 28.2% discontinued therapy, more than half of them because of side-effects. Conclusions. The womens primary reason for starting HRT was climacteric complaints. Sideeffects were normal and constituted the major reason for...If you want to get a full essay, order it on our website: Ordercustompaper.com



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